The first non-baseball event at the new Yankee Stadium took place on the evening of Saturday, April 25, 2009, when Senior Pastor Joel Osteen of Lakewood Church held what was dubbed as a "Historic Night of Hope" Christian prayer service.
A New York University graduation ceremony was held on May 13, 2009, with the address being delivered by the former New York Senator Hillary Clinton and U.S. Secretary of State. The 2010 NYU ceremony featured Alec Baldwin as a speaker. President Bill Clinton spoke at the 2011 ceremony.
In 2014, Yankee Stadium housed the Double-A and Triple-A New York City High School Public School Athletic League Championship. In 2011, it became home to the PSAL Football City Conference Championship.